MEASUREMENT OF SERUM BIOCHEMICAL LIVER PARAMETERS AND HCV RNA LEVELS FOR DETECTION THE SEVERITY OF HEPATITIS C VIRUS-ASSOCIATED HEPATOCELLULAR CARCINOMA

Hepatitis C virus (HCV) is one of the leading causes chronic liver disease. Hepatocellular carcinoma (HCC) a major complication associated with HCV infection, significant mortality and morbidity rates. This study aimed to measure biochemical parameters RNA levels for detection severity hepatitis virus- hepatocellular carcinoma. The was conducted on 100 patients, ages ranging from 36 68 years patients grouped into four groups. The 1 st group served as control (n= 25),the second (n=25): Virus, third HCV-associated HCC fourth After removal tumor resection. Serum samples were collected studied patients. Liver function enzymes (ALT, AST, Alkaline phosphatase) another (Albumin Total bilirubin) tested all groups. The results showed that HCC, after groups had an increase in enzymes, decrease albumin levels, total bilirubin which indicate damage liver. Viral loads indicated males infected higher than females significantly increased highly patients. Conclusively, are